منابع مشابه
Combining antiangiogenic therapy and radiation in nasopharyngeal carcinoma
Radiation therapy is the primary treatment in nasopharyngeal carcinoma (NPC), and the effect of radiation therapy is strongly related to the oxygen content of cancer cells. That means, it is imperative to balance the interactions between radiotherapy and anti-angiogenesis therapy when giving combination therapy to improve clinical outcomes. The complicated mechanisms between antiangiogenic agen...
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Antiangiogenic therapy is based upon the fact that tumor vasculature forms from genetically stable endothelial cells that grow into the genetically unstable tumor. Endothelial cells represent attractive targets for therapy, because tumor expansion depends on angiogenesis and endothelial cells are less likely to develop drug resistance than the tumor cells that surround them (1, 2). The findings...
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ژورنال
عنوان ژورنال: Investigative Radiology
سال: 2012
ISSN: 0020-9996
DOI: 10.1097/rli.0b013e31823a82f6